PROVIDENCE HEALTH & SERVICES-OREGON D/B/A PROVIDENCE PORTLAND MEDICAL CE NTER;ADURO BIOTECH
发明人:
LAUER, PETER M.,BAHJAT, KEITH
申请号:
CA2818353
公开号:
CA2818353A1
申请日:
2011.11.17
申请国别(地区):
CA
年份:
2012
代理人:
摘要:
The present invention relates to methods of inducing a T-cell response against a EGFRvIII in a subject. These method comprise administering to a subject a composition which expresses at least one immunogenic polypeptide, the amino acid sequence of which comprise a plurality of EGFRvIII polypeptide sequences, the sequence of which each comprise EEKKGNYV (SEQ ID NO: 3), and/or administering the polypeptide itself.