Russell P. Rother,Douglas L. Sheridan,Paul P. Tamburini,Yuchun Zhang
申请号:
US15262697
公开号:
US09963503B2
申请日:
2016.09.12
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present disclosure relates to, inter alia, antibodies, or antigen-binding fragments thereof, that bind to C5a and to use of the antibodies in methods for treating or preventing complement-associated disorders such as, but not limited to, atypical hemolytic uremic syndrome, age-related macular degeneration, rheumatoid arthritis, sepsis, severe burn, antiphospho lipid syndrome, asthma, lupus nephritis, Goodpasture's syndrome, and chronic obstructive pulmonary disease.