Pcsk9 antagonists

• 收藏
• 分享

专利权人:

NOVARTIS AG

发明人:

COHEN STEVEN B,RUE SARAH,LI JUN,YOWE DAVID

申请号：

NZ62543310

公开号：

NZ625433A

申请日:

2010.12.10

申请国别(地区):

NZ

年份:

2015

代理人:

摘要：

Disclosed is an antibody that binds to proprotein convertase subtilisinlkexin type 9 (PCSK9), wherein the antibody comprises the CDRs/VH and VL chains of the sequences as defined in the specification, and wherein the antibody: a) does not block PCSK9 binding to the low density lipoprotein receptor (LDLR) and b) inhibits PCSK9-mediated degradation of LDLR.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/