James T. Dalton,Mitchell S. Steiner,Ramesh Narayanan,Sunjoo Ahn
申请号:
US14293632
公开号:
US09622992B2
申请日:
2014.06.02
申请国别(地区):
US
年份:
2017
代理人:
摘要:
This invention relates to the treatment of breast cancer in a subject, for example a female subject. Including methods of: treating metastatic breast cancer refractory breast cancer AR-positive breast cancer AR-positive refractory breast cancer AR-positive metastatic breast cancer AR-positive and ER-positive breast cancer triple negative breast cancer advanced breast cancer breast cancer that has failed SERM (tamoxifen, toremifene), aromatase inhibitor, trastuzumab (Herceptin, ado-trastuzumab emtansine), pertuzumab (Perjeta), lapatinib, exemestane (Aromasin), bevacizumab (Avastin), and/or fulvestrant treatments metastasis in a subject suffering from breast cancer comprising administering to the subject a therapeutically effective amount of a selective androgen receptor modulator (SARM) compound.