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Blood vessel stent of amidoglucosan polysaccharide loaded with CD133 antibody and its preparation method
专利权人:
Shixuan Zhang
发明人:
Shixuan Zhang,Jinghan Sui,Hong Zhao,Dazhi Yang
申请号:
US12602976
公开号:
US08414873B2
申请日:
2008.10.10
申请国别(地区):
US
年份:
2013
代理人:
摘要:
A blood vessel metal stent coating of amidoglucosan polysaccharide loaded with antibody comprises carrier material composed of chitosan and inartificial degradable acidic amidoglucosan polysaccharide and the effective dose of CD133 antibody loaded in the carrier material. The blood vessel metal stent coating is manufactured with self-assemble method to fix the CD133 antibody in the carrier material of the coating. The coating has good biocompatibility, water retention property, flexibility, flush resistance and bio-stability, and can specifically capture the vascular endothelial progenitor cells in human peripheral blood, and differentiate into vascular endothelial cells. The process would accelerate endothelialization to repair injured vessel caused and prevent restenosis and thrombosis efficiently.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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