PROBLEM TO BE SOLVED: To provide a vaccine pharmaceutical composition that can be used ubiquitously to induce humoral immunity to various antigens and exhibits an excellent effect of inducing antibody production.SOLUTION: The present invention is a vaccine pharmaceutical composition for inducing humoral immunity, in which the vaccine pharmaceutical composition includes an antigen, and an immunity induction promoter that is a bisphosphonate.SELECTED DRAWING: NoneCOPYRIGHT: (C)2016,JPO&INPIT【課題】様々な抗原に対する液性免疫誘導のために普遍的に使用可能であり、高い抗体産生誘導効果を発揮するワクチン医薬組成物を提供する。【解決手段】液性免疫誘導のためのワクチン医薬組成物であって、抗原と、ビスホスホネート剤である免疫誘導促進剤とを含むワクチン医薬組成物。【選択図】なし