A process for the purification of influenza virus or derivative thereof comprising the steps of:providing a source having influenza virus or derivative thereof；optionally subjecting the source to a prepurification step；followed by at least one chromatographic step on chromatographic materials selected from the group consisting of porous particles having mean pore sizes of at least 20 nm, perfusion particles, gel-in-a-shell particles, tentacle like particles, membrane adsorbers, and monoliths；collecting eluting influenza virus or derivatives thereof containing fractionswith the proviso that sulfuric ester of cellulose or cross-linked polysaccharides are excluded.
