An ampoule with an integrated piezoelectric unit for use with a personal nebulizer or vaporizing unit with a mouthpiece. The substance to be vaporized is contained in the ampoule which is inserted into the unit, where the substance is vaporized through the integrated piezoelectric transducers or atomizers providing sonic or ultrasonic vibration. The substance to be vaporized may include a variety of therapeutic, homeopathic, or naturopathic formulations, remedies, or serums.