Certain example embodiments relate to techniques for using coherent electromagnetic (EM) waves to treat tumors and/or other growths. In certain example embodiments, a growth is imaged. Based on this image, a holographic plate is prepared. Coherent electromagnetic waves are then focused on the holographic plate so that a holographic image of the growth is formed on the actual growth. Magnetic particles may be injected at or proximate to the growth and captured in the EM field corresponding to the holographic image such that these injected particles are caused to congregate in and/or on the growth. In certain example embodiments, bombarding of the growth with the injected particles may help damage or destroy the tumor. In certain example embodiments, the particles, once attached to and/or embedded in the actual growth may be irradiated (e.g., using a microwave or other energy source) so as to further damage or destroy the growth.