The present invention relates to a kind of polypeptides comprising or by amino acid sequence SEQ sequence numbers: 1, for treating or preventing inflammatory disease.The invention also includes the nucleic acid sequence of polypeptide of the invention, carrier includes that nucleic acid and host cell of the invention include nucleic acid sequence and/or carrier of the invention, for treating or preventing inflammatory disease.Include polypeptide the present invention also relates to pharmaceutical composition, nucleic acid sequence, carrier or host cell it is of the invention and pharmaceutically acceptable carrier composition, for treating inflammatory disease.