Berger, Andreas,Macher, Ingolf,Decristoforo, Martin
申请号:
AU2007304867
公开号:
AU2007304867B2
申请日:
2007.10.03
申请国别(地区):
AU
年份:
2013
代理人:
摘要:
A process for the preparation of 14-O-[(N-(3-methyl-2-amino-butyryl-piperidinyl)sulfanyl) acetyl]mutilinsof formula (I) feasible for large-scale production of high purity products,and wherein the carbon atom at the piperidine ring attached to the sulphur atomis either in the (S)-configuration or in the (R)-configuration, and a new crystallineform of 14-O-[(N-3-methyl-2-(R)-amino-butyryl-piperidine-3(S)-yl)sulfanyl)acetyl]mutilin-hydrochloride.