an-a5ß1 antibodies, isolated nucleic acid molecule, antibody expression vector, method of producing an antibody, compositions, method for detecting a5ß1 protein, use of antibody, method for inhibiting angiogenesis and / or vascular permeability or leakage, methods to treat cancer, to treat eye disease, and to treat autoimmune disease
GREGORY D. PLOWMAN,WEI-CHING LIANG,WEILAN YE,YAN WU
申请号：
BRPI0816049
公开号：
BRPI0816049A2
申请日:
2008.09.25
申请国别(地区):
BR
年份:
2019
代理人:
摘要：
The present invention relates to the use of VEGF antagonists and a novel anti-&alpha；5&bgr；1 antibody for treating cancer and inhibiting angiogenesis and/or vascular permability, including inhibiting abnormal angiogenesis in diseases. The present invention also relates to compositions and kits comprising novel anti-&alpha；5&bgr；1 antibodies and methods of making and using them.
