Mastalerz, Harold,Wittman, Mark D,Zimmermann, Kurt,Saulnier, Mark G,Velaparthi, Upender,Vyas, Dolatrai M,Zhang, Guifen,Johnson, Walter Lewis,Frennesson, David B,Sang, Xiaopeng,Liu, Peiying,Langley, Da
申请号：
NO20090025
公开号：
NO342385B1
申请日:
2009.01.05
申请国别(地区):
NO
年份:
2018
代理人:
摘要：
Pirrolotriazina kinase inhibitors. The present invention relates to compounds of Formula 1 and sais pharmacologically acceptable of the same. The compounds of the formula 1 inhibit the activity of tyrosine kinase, thereby making them useful as anti-cancer agents and for the treatment of Alzheimer's disease.(I) Oppfinnelsen tilveiebringer forbindelser med formel I og farmasøytisk akseptable salter derav. Forbindelsene med formel I hemmer tyrosinkinase-aktivitet som derved gjør dem nyttige som anticancer-midler og for behandling av Alzheimer's sykdom.
