Knuehl, Christine,Hock, Bjoern,Hofmeister, Robert,Beste, Gerald,Revets, Hilde Adi Pierrette,Verdonck, Frank Kamiel Delphina,Cornelis, Sigrid Godelieve Victor
申请号：
AU2015264802
公开号：
AU2015264802A1
申请日:
2015.12.01
申请国别(地区):
AU
年份:
2016
代理人:
摘要：
#$%^&*AU2015264802A120160107.pdf#####H:\szp\Interwoven\NRPortbl\DCC\SZP\8859582 1docx-1/12/2015 ABSTRACT The present disclosure relates to amino acid sequences that are directed against (as defined herein) HER3, as well as to compounds or constructs, and in particular proteins and polypeptides, that comprise or essentially consist of one or more such amino acid sequences (also referred to herein as "amino acid sequences of the invention", "compounds of the invention", and "polypeptides of the invention", respectively). The disclosure also relates to nucleic acids encoding such amino acid sequences and polypeptides (also referred to herein as "nucleic acids of the invention" or "nucleotide sequences of the invention") to methods for preparing such amino acid sequences and polypeptides to host cells expressing or capable of expressing such amino acid sequences or polypeptides to compositions, and in particular to pharmaceutical compositions, that comprise such amino acid sequences, polypeptides, nucleic acids and/or host cells and to uses of such amino acid sequences or polypeptides, nucleic acids, host cells and/or compositions, in particular for prophylactic, therapeutic or diagnostic purposes, such as the prophylactic, therapeutic or diagnostic purposes mentioned herein.
