DOSCHAK, MICHAEL,YANG, YANG,BHANDARI, KRISHNA HARI
申请号：
CA2883707
公开号：
CA2883707A1
申请日:
2013.08.28
申请国别(地区):
CA
年份:
2014
代理人:
摘要：
Described herein is insulin, an insulin-like growth factor, parathyroid hormone, a fragment of parathyroid hormone, or a parathyroid hormone related protein that includes at least one bone targeting moiety, wherein the bone targeting moiety is covalently bonded to the peptide. Also described herein are the methods of making these compositions that prevent or treat conditions associated with bone loss and preventing bone fractures, and/or the inability to initiate de novo bone turnover and stimulate bone fracture repair.
