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Method of Manufacturing Enteric Seamless Soft Capsule
专利权人:
FUJI CAPSULE CO.; LTD.
发明人:
MASUDA, Koji,NISHIMURA, Naoki,HAYANO, Akihiko,SHIMOKAWA, Yoshiyuki,KATO, Kenji
申请号:
SG11201702752R
公开号:
SG11201702752RA
申请日:
2015.10.06
申请国别(地区):
SG
年份:
2017
代理人:
摘要:
An object is to provide a method of manufacturing a seamless soft capsule that is enteric and excellent in formulation properties. An enteric seamless soft capsule is manufactured by the following steps (a) and (b): (a) preparing an enteric capsule shell liquid comprising gelatin and low methoxy pectin having a degree of esterification of 0 to 40% and a degree of amidation of 0 to 25%, the enteric capsule shell liquid having a viscosity at 50°C of 60 to 127 mPa€¢s; and (b) encapsulating capsule fills with the enteric capsule shell liquid prepared in the step (a) by dripping. Preferably, the jelly strength of the gelatin is 180 to 330 Bloom, an aqueous solution of the low methoxy pectin at a concentration of 2 mass% has a viscosity at 35°C of 8 to 15 mPa€¢s, and the enteric capsule shell liquid comprises 10 to 20 parts by mass of the low methoxy pectin per 100 parts by mass of gelatin.
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