פרודרגים תיואסטר של מקרוציקלים כמעכבי היסטון דהאצטילאז

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专利权人:

PISCOPIO Anthony D.;ONKURE INC.

发明人:

PISCOPIO Anthony D.

申请号：

IL26315918

公开号：

IL263159D0

申请日:

2018.11.20

申请国别(地区):

IL

年份:

2018

代理人:

摘要：

The present invention provides a novel macrocyclic prodrug compound of general Formula (I), a pharmaceutical composition comprising a compound of Formula (I), and a method for treating diseases mediated by HDAC enzymes by administering a compound of Formula (I), wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, A and Z are defined herein.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/