Inhibiting surface enhanced crystallization of amorphous pharmaceuticals with ultrathin coatings

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专利权人:

Lian Yu

发明人:

Lian Yu,Melgardt M. De Villiers,Tian Wu

申请号：

US12053244

公开号：

US09254266B2

申请日:

2008.03.21

申请国别(地区):

US

年份:

2016

代理人:

摘要：

The present invention provides surface-stabilized amorphous pharmaceuticals comprising an amorphous pharmaceutical substrate coated with a biocompatible immobilizing material. Amorphous pharmaceutical substrates that are prone to surface enhanced crystallization benefit from the present coatings. The coated amorphous pharmaceuticals of the present invention maintain their amorphous state and, therefore, their solubility over extended periods of time, relative to uncoated pharmaceuticals.

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中国工程科技知识中心

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