Methods for treating Fibrodysplasia Ossificans Progressiva (FOP) are provided in which a subject having FOP is administered an effective regime of an antibody against Activin B, BMP9 or BMP10.本發明提供用於治療進行性骨化性纖維發育不良(FOP)之方法,其中投與患有FOP之個體針對活化素B、BMP9或BMP10之抗體的有效療程。