ブロック状細胞工学用支持体の製造方法
- 专利权人:
- 株式会社ジーシー
- 发明人:
- 山本 克史,山中 克之,須田 洋子,坂井 裕大,金子 正
- 申请号：
- JP2008078388
- 公开号：
- JP5280078B2
- 申请日:
- 2008.03.25
- 申请国别(地区):
- JP
- 年份:
- 2013
- 代理人:
- 摘要：
PROBLEM TO BE SOLVED: To provide a production method of a cell-engineering block-like support used as a substitute for biotissue, having superior morphological stability, allowing a user to seed and/or culture cells in its interior and consisting of a bioabsorbable polymer material having a wide void.
SOLUTION: The sheet-like bioabsorbable polymer material with the thickness of 0.01-1 mm is brought together irregularly, put in a mold and pressurized and heated to produce this cell-engineering block-like cell support having a continuous amorphous void occupying 10-90% in porosity. Preferably, the sheet-like bioabsorbable polymer material has pores of 5-100 &mum produced by dissolving the bioabsorbable polymer material in organic solvent, and freeze-drying it, or pores with the diameter of 0.1-3 mm is formed on the sheet-like bioabsorbable polymer material produced by dissolving the bioabsorbable polymer material in the organic solvent and drying it. It is preferable to use the oblong sheet-like bioabsorbable polymer material with the length of 5-50 mm, the width of 0.1-20 mm and the thickness of 0.01-1 mm.
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- 来源网站：
- 中国工程科技知识中心
