The present disclosure relates, in some embodiments, to a dental prosthesis and methods of use thereof. According to some embodiments, a dental prosthesis includes a dental implant surgical guide, a prosthesis base, a prosthesis cover, at least one implant configured to be inserted through the dental implant surgical guide and the prosthesis base into a dental surgical site and at least one implant fastener configured to attach to the at least one implant. A prosthesis base may include: a base bottom configured to sit adjacent to a dental surgical site, and a base top including a base recess, the base recess including at least one base aperture. In some embodiments, the dental implant surgical guide is configured to sit within a base recess. A prosthesis cover, in some embodiments, may include a cover recess configured to encapsulate at least a portion of the dental implant surgical guide within the base recess.