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COMPOSITIONS PERMETTANT DE MODULER L'EXPRESSION DE C90RF72
专利权人:
INC.;ISIS PHARMACEUTICALS
发明人:
BENNETT, FRANK C.,FREIER, SUSAN M.,SWAYZE, ERIC E.,RIGO, FRANK
申请号:
CA2888486
公开号:
CA2888486A1
申请日:
2013.10.15
申请国别(地区):
CA
年份:
2014
代理人:
摘要:
Disclosed herein are compositions and methods for reducing expression of C90RF72 mRNA and protein in an animal with C90RF72 specific inhibitors. Such methods are useful to treat, prevent, or ameliorate neurodegenerative diseases in an individual in need thereof. Such C90RF72 specific inhibitors include antisense compounds. Examples of neurodegenerative diseases that can be treated, prevented, and ameliorated with the administration C90RF72 specific inhibitors include amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD), corticalbasal degeneration syndrome (CBD), atypical Parkinsonian syndrome, and olivopontocerellar degeneration (OPCD).
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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