A surgical stapling apparatus is disclosed which comprises a tissue stop configured to inhibit tissue from flowing out of the distal end of the stapling instrument as the tissue is being stapled and/or incised. Also disclosed is a surgical stapling apparatus comprising one or more interruptions, or absent staple cavities, in the rows of staple cavities defined therein. Also disclosed is a surgical stapling apparatus comprising a channel configured to receive tissue and/or another surgical instrument therein. In at least one instance, such a stapling apparatus could comprise staple cavities on one side of a longitudinal knife slot and no staple cavities on the other side of the knife slot. Further disclosed are methods for using the surgical stapling devices disclosed herein.