A system for the articulated culture of microorganisms (microalgae) with a high content of proteins, vitamins, pigments, and the like, at least comprising: m production modules each divided into at least two stages, each stage consisting of n tube nests (batteries of tubes) each with n tubes alternating with n' degassing modules (on line degassers), at each stage there being associated a tower acting as a temperature control means, the distribution of the n' on line degassers being differentiated in the sense of giving rise to exponentially variable gradients in the spacing between pairs of neighboring degassers (ni-1-ni), and means for the control and regulation of temperature, PH, concentration of dissolved oxygen, cell concentration and tube nest integrity, the said means being controlled by a central processing unit.