A method for imaging episcleral vessels in an eye includes injecting the eye with a contrast agent, positioning an imaging probe proximate to a limbus of the eye, acquiring a plurality of images along a circumference of the limbus and applying a vessel segmentation algorithm to the plurality of images to quantify episcleral diameter and density in real-time. A system for imaging episcleral vessels in an eye includes a processing unit operably connected to an imaging probe and a visual feedback device. In certain embodiments, the contrast agent includes fluorescein. In certain embodiments, the episcleral diameter and density is displayed in an image on a visual feedback device. In certain embodiments, the method is part of a treatment for relieving intraocular pressure in an eye that can include the steps of identifying a target treatment area based on the image and applying a MIGS treatment in the target treatment area. A microendoscope device for imaging episcleral vessels in an eye includes a handpiece and an intraocular tip, the intraocular tip having ultrasound or confocal laser imaging features.
