Composés de type carboxamide et leur utilisation comme inhibiteurs des calpaines

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专利权人:

ABBVIE DEUTSCHLAND GMBH & CO KG

发明人:

申请号：

EP11195099.4

公开号：

EP2439205B1

申请日:

2007.12.28

申请国别(地区):

EP

年份:

2015

代理人:

摘要：

The present invention relates to novel carboxamide compounds and their use for the manufacture of a medicament. The carboxamide compounds are inhibitors of calpain (calcium dependant cysteine proteases). The invention therefore also relates to the use of these carboxamide compounds for treating a disorder associated with an elevated calpain activity. The carboxamide compounds are compounds of the general formula I in which R 1 , R 2 , R 3a , R 3b , W, V and X have the meanings mentioned in the claims and the description, the tautomers thereof and the pharmaceutically suitable salts thereof.

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