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Composés de type carboxamide et leur utilisation comme inhibiteurs des calpaines
专利权人:
ABBVIE DEUTSCHLAND GMBH & CO KG
发明人:
申请号:
EP11195099.4
公开号:
EP2439205B1
申请日:
2007.12.28
申请国别(地区):
EP
年份:
2015
代理人:
摘要:
The present invention relates to novel carboxamide compounds and their use for the manufacture of a medicament. The carboxamide compounds are inhibitors of calpain (calcium dependant cysteine proteases). The invention therefore also relates to the use of these carboxamide compounds for treating a disorder associated with an elevated calpain activity. The carboxamide compounds are compounds of the general formula I in which R 1 , R 2 , R 3a , R 3b , W, V and X have the meanings mentioned in the claims and the description, the tautomers thereof and the pharmaceutically suitable salts thereof.
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