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Compounds and their use
专利权人:
ORCHID CHEMICALS AND PHARMACEUTICALS LIMITED
发明人:
ARAVIND APPU,SENTHIKUMAR UDAYAMPALAYAM PALANISAMY,MANEESH PAUL-SATYASEELA
申请号:
AP2013006947
公开号:
AP2013006947A0
申请日:
2011.11.25
申请国别(地区):
AP
年份:
2013
代理人:
摘要:
Described herein are compounds and their use in the treatment of infections. The compound of formula (I), their derivatives, analogs, tautomeric forms, stereoisomers, polymorphs, solvates, pharmaceutically acceptable salts and pharmaceutical compositions described herein are also useful as beta-lactamase inhibitors, which restore or enhance the antibiotic spectrum of a suitable antibiotic agent. The compounds of formula (I) act as inhibitors of beta-lactamases. These compounds restore/potentiate the activities of beta-lactam antibiotics against carbapenemases. These compounds find use in diagnostic method for detecting beta-lactamases. Formula (I)
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