Kenneth B. Stokes,Michael J. Ebert,Christopher M. Hobot
申请号：
US10386967
公开号：
US08673339B2
申请日:
2003.03.11
申请国别(地区):
US
年份:
2014
代理人:
摘要：
A biostable polymeric substrate of an implantable medical device unit includes a demand-release bioactive composition including one or more bioactive agents covalently bound to surface-modifying end groups of the substrate. Certain cellular activities, in proximity to the polymeric substrate, release substances reacting with the end groups such that the end groups release the one or more bioactive agents, which modify the certain cellular activities.
