Imidazolyl pyrimidine compounds substituted with amino - indolilo, inhibitors of protein kinase Syk； Compounds, Intermediates, Pharmaceutical formulations containing them, for use in the treatment of diseases such as COPD, Asthma, allergic rhinitis, among others.
DAHMANN, GEORG,DOLLINGER, HORST,GNAMM, CHRISTIAN,FIEGEN, DENNIS,HOFFMANN, MATTHIAS,LAMB, DAVID, JAMES,KLICIC, JASNA,SCHNAPP, ANDREAS
申请号：
CL2014002732
公开号：
CL2014002732A1
申请日:
2014.10.10
申请国别(地区):
CL
年份:
2015
代理人:
摘要：
The invention relates to new amino-indole-substituted imidazolyl-pyrimidines of formula 1 wherein R1, R2, R3, R4 and R5 are defined as in claim 1 and pharmaceutically acceptable salts thereof and the use of these compounds for the preparation of a medicament for treating a disease selected from asthma, COPD, rheumatoid arthritis, specific lymphomas and specific diseases of the nervous system.Compuestos derivados de imidazolil-pirimidina sustituida con amino-indol, inhibidores de proteína quinasa Syk； compuestos intermediarios, composición farmacéutica que los comprende； y su uso en el tratamiento de enfermedades tales como asma, EPOC, rinitis alérgicas, entre otras
