A biopsy tissue sampling treatment instrument 1 includes a stem portion 12 configured to be inserted into a body and punctured in a body tissue 100 a protruding portion 14 disposed around the stem portion 12 and a stopper portion 13 configured to abut a surface of the body tissue 100 and define an amount of puncture depth of the stem portion 12 and the protruding portion 14 punctured in the body tissue 100. Consequently, the biopsy tissue sampling treatment instrument increases holding capacity for the living tissue to be extracted, allows living tissue to be extracted in sufficient sampling quantities, and makes it easy to take samples of living tissue at an intended depth in tissue.