The present application relates to a system and method for measuring a pulse wave of a subject. The system comprises: a first sensor array and a second sensor array for respectively sensing a corresponding pulse wave of a first and a second artery of the subject, each of the first sensor array and the second sensor array comprising a plurality of sensors for respectively acquiring a plurality of first signals indicating a vibration of the skin a deriving unit configured to derive, for each of the first sensor array and the second sensor array, a second signal representing the corresponding pulse wave from the plurality of first signals and a first calculating unit configured to calculate a pulse transit time between the first artery and the second artery from the second signal derived for the first sensor array and the second signal derived for the second sensor array. An embodiment of this invention can improve accuracy of pulse wave measurement.