CHEN, Christine Hiu-tung,CHEN, Zhuoliang,DORE, Michael,FORTANET, Jorge Garcia,KARKI, Rajesh,KATO, Mitsunori,LAMARCHE, Matthew J.,PEREZ, Lawrence Blas,SMITH, Troy Douglas,WILLIAMS, Sarah,GIRALDES, John
申请号：
LT15703321
公开号：
LT3094628T
申请日:
2015.01.16
申请国别(地区):
LT
年份:
2018
代理人:
摘要：
in which p, q, Y1, Y2, R1, R2a, R2b, R3a, R3b, R4a, R4b, R5a, R5b, R7 and R8 are defined in the Summary of the Invention； capable of inhibiting the activity of SHP2. The invention further provides a process for the preparation of compounds of the invention, pharmaceutical preparations comprising such compounds and methods of using such compounds and compositions in the management of diseases or disorders associated with the aberrant activity of SHP2.
