InGeneron, Inc;Alliance of Cardiovascular Researchers
发明人:
Eckhard ALT,Tahereh KARIMI
申请号:
US15914782
公开号:
US20180264046A1
申请日:
2018.03.07
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Adult stem cells are reprogrammed to form pacemaker cells and Purkinje cells through the sequential activation of SHOX2>;TBX5>;HCN2. These Purkinje cells spontaneously surround and connect with the larger pacemaker cells, thus forming an induced sinoatrial body that produces funny current and can make cardiovascular tissues beat in a manner similar to a natural sinoatrial node.