PARADKAR ANANT,KELLY ADRIAN,COATES PHIL,YORK PETER
申请号:
IN952/DELNP/2011
公开号:
IN2011DN00952A
申请日:
2011.02.08
申请国别(地区):
IN
年份:
2012
代理人:
摘要:
The present invention provides a method of producing a co-crystal, the method comprising the steps of, providing a first substance and a second substance, wherein the first and second substances are compatible to form a co-crystal, mixing said first and second substances together, and exposing the mixture of said first and second substances to prolonged and sustained conditions of pressure and shear, sufficient to form a co-crystal of said first and second substance. The prolonged and sustained conditions of pressure and shear are preferably applied in an extrusion process. Associated compositions and uses thereof are also provided.