ADVENCHEN LABORATORIES NANJING LTD.;CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.
发明人:
Xunqiang Wang,Yadong Miu,Min Zhou,Shanchun Wang,Ling Yang,Wei Shi
申请号:
US16383288
公开号:
US20190298712A1
申请日:
2019.04.12
申请国别(地区):
US
年份:
2019
代理人:
摘要:
The present application provides a quinoline derivative against non-small cell lung cancer. 1-[[[4-(4-fluoro-2-methyl)-1H-indol-5-yl)oxy-6-methoxyquinolin-7-yl]oxy]methyl]cyclopropylamine or a pharmaceutically acceptable salt thereof provided by the present application can be used for the treatment of non-small cell lung cancer, and relative to placebo, can significantly improve non-small cell lung cancer patients without progression of survival. 1-[[[4-(4-fluoro-2-methyl-1H-indol-5-yl)oxy-6-methoxyquinolin-7-yl]oxy]methyl]cyclo propylamine or a pharmaceutically acceptable salt thereof provided by the present application can be used for the treatment of lung adenocarcinoma, and relative to placebo, can significantly improve lung adenocarcinoma patients without progression of survival.