A microjet drug delivery system includes a pressure chamber which has a predetermined storing space and of which a closed inner portion is hermetically filled with water, a drug chamber which is disposed adjacent to the pressure chamber and is configured to store a drug solution in a predetermined storing space and where a micro nozzle ejecting the drug solution as a microjet to an outside is formed at one side thereof, an elastic membrane which is disposed between the pressure chamber and the micro drug chamber, and a laser unit which irradiates the pressure driving liquid stored in the pressure chamber with laser to generate bubble in the pressure driving liquid. The laser unit irradiates a laser beam having an oscillation wavelength range of 2.8 μm to 3.0 μm, and in particular, an Er:YAG laser having a wavelength of 2.94 μs (2940 nm) is used.
