Multispecific antigen-binding molecule having blood coagulation factor VIII (FVIII) cofactor function alternative activity and pharmaceutical preparation containing the molecule as an active ingredient
We succeeded in finding a bispecific antibody that does not elevate the FIX activation inhibitory activity and elevates the FVIII cofactor alternative activity.FIX活性化阻害活性は上昇させず、かつFVIII補因子機能代替活性を上昇させる二重特異性抗体を見出すことに成功した。