The present invention relates to a composition useful for the treatment of lipid metabolism disorders, comprising one or more of the following active ingredients: (a) extract of rice fermented with Monascus purpureus, (b) at least one omega-3 fatty acid, (c) L-camitine or a salt thereof and one or more of the following active ingredients: (d) at least one policosanol or a natural extract containing policosanols (e) resveratrol or a natural extract containing resveratrol (f) Coenzyme Q10 and (g) at least one vitamin.本發明關於一種用於治療脂質代謝失調之組成物,其包含下述活性成分之一或多種:(a)經紫紅麴黴醱酵之米的萃取物;(b)至少一種ω-3脂肪酸;(c)L-肉鹼或其鹽;及下述活性成分之一或多種:(d)至少一種甘蔗原素或含有甘蔗原素的天然萃取物;(e)白藜蘆醇或含有白藜蘆醇的天然萃取物;(f)輔酶Q10;及(g)至少一種維生素。