The invention relates a method of manufacturing magnesium alloy implant material with selective-stage biodegradation. It comprises the steps of melting a magnesium (Mg) ingot and a zinc (Zn) ingot to form a Mg-Zn alloy billet, and cooling and shaping the Mg-Zn alloy billet to form an alloy material performing a strain induced melt activation process for generating a SIMA structure on the alloy material bombarding and implanting a metal element on a surface of the alloy material to distort the lattice of the surface and form a ion implantation layer immersing the alloy material in a alkaline solution and transforming the ion implantation layer into a inorganic surface layer by a hydrothermal treatment for getting a magnesium alloy implant material with cell attachment and three-stage biodegradation characteristics.本發明係有關於一種可選擇性階段降解之鎂合金植體材料製備方法,係包含將鎂(Mg)錠與鋅(Zn)錠熔煉成鎂鋅合金胚料,並冷卻塑形成一合金材料;接續將合金材料進行一應變導引熔漿活化作用(Strain Induced Melt Activated, SIMA),以使合金材料具有SIMA組織;再進行轟擊佈植一金屬元素於合金材料之表面,使表面之晶格扭曲變形,形成一離子佈植層;以及將合金材料浸置於一鹼液中,並利用水熱法使離子佈植層形成一無機表面層,以獲得一具細胞貼附性與三階段降解特性之鎂合金植體材料。(S1)‧‧‧步驟一(S2)‧‧‧步驟二(S3)‧‧‧步驟三(S4)‧‧‧步驟四
