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INJECTABLE STERILE AQUEOUS FORMULATION BASED ON CROSSLINKED HYALURONIC ACID AND ON HYDROXYAPATITE FOR THERAPEUTIC USE
专利权人:
发明人:
GAVARD MOLLIARD SAMUEL
申请号:
IN718/MUMNP/2015
公开号:
IN2015MN00718A
申请日:
2015.04.01
申请国别(地区):
IN
年份:
2016
代理人:
摘要:
The subject matter of the present invention is a ready to use resorbable injectable sterile aqueous formulation used for therapeutic purposes in the form of a particulate cohesive viscoelastic gel comprising i) crosslinked hyaluronic acid or a salt thereof at a concentration of between 1% and 4% (weight/volume) the crosslinking carried out making it possible to obtain a crosslinked hyaluronic acid based gel having a structure termed cohesive and ii) hydroxyapatite at a concentration of between 10% and 70% (weight/volume) said hydroxyapatite being in the form of particles having an average size of less than or equal to 650 �m wherein said injectable sterile aqueous formulation has viscoelastic properties such that Tand at the frequency of 1 Hz is less than or equal to 0.60.
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中国工程科技知识中心
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