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uses of at least one polypeptide, uses of at least one recombinant vector, isolated antigen presenting cell, isolated t cell, method for inducing immunity, methods for detecting cancer and reagent for detecting cancer
专利权人:
TORAY INDUSTRIES; INC.
发明人:
FUMIYOSHI OKANO,MASAKI SHIMIZU,TAKANORI SAITO
申请号:
BRPI0910513
公开号:
BRPI0910513A2
申请日:
2009.07.10
申请国别(地区):
BR
年份:
2015
代理人:
摘要:
An immunity-inducing agent comprising as an effective ingredient(s) at least one polypeptide selected from the following polypeptides, the polypeptide(s) having an immunity-inducing activity/activities, or as an effective ingredient(s) a recombinant vector(s) which comprise(s) a polynucleotide(s) encoding the polypeptide(s) and is/are capable of expressing the polypeptide(s) in vivo can be used for therapy and/or prophylaxis of cancer: (a) a polypeptide consisting essentially of not less than 7 consecutive amino acids in any one of the amino acid sequences shown in the odd number IDs of SEQ ID NOs:3 to 95 in SEQUENCE LISTING; (b) a polypeptide having a sequence identity of not less than 90% with the polypeptide (a) and consisting essentially of not less than 7 amino acids; and (c) a polypeptide comprising the polypeptide (a) or (b) as a partial sequence thereof. Further, since the above polypeptide(s) react(s) with antibodies existing specifically in serum of a cancer patient, it is possible to detect cancer in a living body by measuring the antibodies in a sample.
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