DILUENT FOR RECONSTITUTION OF LYOPHILIZED PROTEINS

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专利权人:

发明人:

SRIPAD GHANWAR,Hemanth Nandigala,Murali Tummuru

申请号：

IN1693/CHE/2010

公开号：

IN2010CH01693A

申请日:

2010.06.17

申请国别(地区):

IN

年份:

2016

代理人:

摘要：

The present invention is for a pharmaceutical composition of lyophilized urate oxidase drug product with a diluent wherein the diluent comprises of propylene glycol and poloxamer 188 in the ratio of 9:1, which aggregate free, and physically stable solution after reconstitution. The diluent is a combination of GRAS listed Propylene Glycol and low amount of Polaxamer. After reconstitution of lyophilized powder of Urate Oxidase with the diluent provides an aggregate free, stable and active solution for at least 0-4h at 4�C or at 0-4h at 25�C.

来源网站：

中国工程科技知识中心

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