Allergen-binding IgE monoclonal antibodies and method for preparing hypoallergens

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专利权人:

Valtion Teknillinen Tutkimuskeskus

发明人:

Niemi, Merja,Rouvinen, Juha,Makinen-Kiljunen, Soili,Takkinen, Kristiina,Jylha, Sirpa,Laukkanen, Marja-Leena,Soderlund, Hans,Haahtela, Tari

申请号：

AU2008211806

公开号：

AU2008211806B2

申请日:

2008.01.29

申请国别(地区):

AU

年份:

2013

代理人:

摘要：

The present invention relates to human IgE antibodies and derivatives thereof, which bind non-continuous planar allergenic epitope, such as in β-lactoglobulin, with high affinity and specificity. The present invention also relates to processes for making and engineering such allergen binding monoclonal antibodies and to methods for using these antibodies and derivatives thereof in the field of immunodiagnostics and immunotherapy.

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