CHEW, Suk Peng,ALBANI, Salvatore,CHOW, Kah-Hoe Pierce,PAN, Lu
申请号：
SG11202003956T
公开号：
SG11202003956TA
申请日:
2018.11.29
申请国别(地区):
SG
年份:
2020
代理人:
摘要：
A method for the prognosis of response to treatment for a patient suffering from cancer, the method comprising: measuring the expression of at least one immune marker in a leukocyte sample taken from the patient with cancer； classifying the patient sample into (i) sustainable responders (SR) to selective internal radiation therapy (SIRT) or (ii) transient/non-responders (TR/NR) to (SIRT) based on expression of the at least one immune marker in relation to a predetermined value and treating sustainable responders (SR) to SIRT or SIRT or a composition comprising SIRT and an immunotherapy. In a preferred embodiment, the method is for the prognosis of response to treatment of a Hepatocellular carcinoma (HCC) patient comprising detecting the co-expression of PD-1 or Tim-3 with CCR5； or expression of PD-1, Tim-3, CXCR6, or combinations thereof in a leukocyte sample taken from the patient.
