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PA14 Novel Imipenem Resistant Pseudomonas aeruginosa specific bacteriophage PA14 and antibacterial composition comprising the same
专利权人:
发明人:
김영주,연영은,한범구,김현일,박철세
申请号:
KR1020170180963
公开号:
KR1020373870000B1
申请日:
2017.12.27
申请国别(地区):
KR
年份:
2019
代理人:
摘要:
The present invention is a novel bacteriophage PA14 having a specific killing ability against antibiotic-resistant Pseudomonas aeruginosa, particularly Imipenem Resistant Pseudomonasaeruginosa (IRPA), an antibiotic composition comprising the bacteriophage, feed composition, feed, disinfectant or cleaning agent, and The present invention relates to a method for preventing or treating an infectious disease caused by imipenem-resistant Pseudomonas aeruginosa comprising administering the bacteriophage to an individual except a human. The method for preventing or treating an infectious disease caused by imipenem-resistant Pseudomonas aeruginosa using bacteriophage PA14 of the present invention has a higher specificity for Pseudomonas aeruginosa, particularly antibiotic-resistant Pseudomonas aeruginosa, and the bacteriophage PA14 infects Pseudomonas aeruginosa. By proliferating in Pseudomonas aeruginosa, lytic activity is excellent, and Pseudomonas aeruginosa killing ability is excellent. In addition, the bacteriophage PA14 of the present invention is not infected with other hosts other than bacteria such as humans, animals and plants, and thus has the advantage of solving the problems of antibiotic resistant bacteria due to the misuse of antibiotics, the residual problem of antibiotics in food, and the problem of a wide range of hosts. have. Therefore, the bacteriophage PA14 of the present invention can be used in various fields in the prevention or treatment of infectious diseases caused by imipenem-resistant Pseudomonas aeruginosa, antibiotic compositions, feed additive compositions, feed, disinfectants, or detergents.본 발명은 항생제 내성 녹농균, 특히 이미페넴 내성 녹농균(Imipenem Resistant Pseudomonas aeruginosa, IRPA)에 특이적인 사멸능을 갖는 신규 박테리오파지 PA14, 상기 박테리오파지를 포함하는 항생용 조성물, 사료 첨가용 조성물, 사료, 소독제 또는 세척제 및 상기 박테리오파지를 인간을 제외한 개체에 투여하는 단계를 포함하는 이미페넴 내성 녹농균에 의한 감염성 질병의 예방 또는 치료 방법에 관한 것이다. 본 발명의 박테리오파지 PA14를 이용한 이미페넴 내성 녹농균에 의한 감염성 질병의 예방 또는 치료 방법은 기존의 항생제 등의 화학물질에 비해 녹농균, 특히 항생제 내성 녹농균에 대한 특이성이 매
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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