Kenneth W. Hance;Connie J. Rogers;Samuel Norbert Breit;David Alexander Brown;Elaine Lanza
发明人:
Samuel Norbert Breit,David Alexander Brown,Kenneth W. Hance,Elaine Lanza,Connie J. Rogers
申请号：
US13504154
公开号：
US20120309697A1
申请日:
2010.10.27
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Methods of diagnosing or prognosing a disease or condition associated with increased or over expression of macrophage inhibitory cytokine-1 (MIC-1) are disclosed. The methods typically involve detecting a change in the amount of MIC-1 in a test body sample from a subject taken at two or more timing points. The change in the amount of MIC-1 may be adjusted for the effect of at least the following factors as appropriate: the gender of the subject, the age of the subject, the body mass index (BMI) of the subject, the subject being a smoker, the subject being a user of NSAIDs, and the waist-to-hip ratio where the subject is female. The methods are particularly suitable for diagnosing or prognosing the presence of one or more colorectal polyp(s).
