Peter Tarcha;Anton G. Clifford;John Toner;Charles Fisher;Keith Cromack;Donald Verlee;Sandra Burke
发明人:
Donald Verlee,Peter Tarcha,Keith Cromack,Sandra Burke,Anton G. Clifford,John Toner,Charles Fisher
申请号：
US10704114
公开号：
US09296011B2
申请日:
2003.11.07
申请国别(地区):
US
年份:
2016
代理人:
摘要：
An interventional device for delivery of beneficial agent to a lumen and methods of loading and manufacture of the same, which include a prosthesis loaded with beneficial agent to provide a controlled dosage concentration of beneficial agent to the lumen. The beneficial agent is loaded onto the prosthesis by a fluid-dispenser having a dispensing element capable of dispensing the beneficial agent in discrete droplets, each droplet having a controlled trajectory. The interventional device has a controlled local areal density of beneficial agent for systemic delivery or delivery to the luminal wall. The local areal density of beneficial agent may be varied along the prosthesis. The interventional device includes overlapping or bifurcated stents having a controlled areal density of beneficial agent.
