The present disclosure relates to systems and processes for inspecting and evaluating qualities of printed regions on substrates, wherein the systems and methods may be configured to eliminate subjective aspects relating to human involvement in performing visual checks when evaluating print quality. The systems may include one or more communication networks connecting one or more sensors with an analyzer. In operation, ink is applied to a substrate to create at least one printed region, and the sensors are configured to inspect the printed region. The sensors may be configured to communicate measurements and/or images to the analyzer. And the analyzer may then calculate one or more quality subscores based on respective measurements and/or images. In turn, a full print quality score may be calculated based on one or more of the quality subscores. The analyzer may then execute a control action based on the full print quality score.