KONIUGATY MAYTANSINOIDU DM1 POŁĄCZONEGO NIEROZŁĄCZALNYM ŁĄCZNIKIEM Z PRZECIWCIAŁEM TRASTUZUMAB I ICH ZASTOSOWANIE W LECZENIU NOWOTWORÓW

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专利权人:

ImmunoGen; Inc.

发明人:

STEEVES, RITA,LUTZ, ROBERT,CHARI, RAVI,XIE, HONGSHENG,KOVTUN, YELENA

申请号：

PL04793896

公开号：

PL1689846T3

申请日:

2004.10.12

申请国别(地区):

PL

年份:

2013

代理人:

摘要：

The present invention discloses a method for targeting maytansinoids to a selected cell population, the method comprising contacting a cell population or tissue suspected of containing the selected cell population with a cell-binding agent maytansinoid conjugate, wherein one or more maytansinoids is covalently linked to the cell-binding agent via a noncleavable linker and the cell-binding agent binds to cells of the selected cell population.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/