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Orally dispersible tablets obtained by compression molding
专利权人:
エティファーム
发明人:
イザベル・デコルテ,エドゥアール・ジェンドロー,ヤン・プレヴォ
申请号:
JP2015547129
公开号:
JP6257642B2
申请日:
2013.12.17
申请国别(地区):
JP
年份:
2018
代理人:
摘要:
Embodiments of the present invention provide an orodispersible tablet having a hardness of 30 to 80 N, and preferably 40 to 75 N, a brittleness less than 1% and preferably less than 0.5%, disintegrating in the mouth within 60 seconds and preferably within 40 seconds, comprising an active ingredient in the form of coated microcrystals or microgranules and a mixture of excipients chosen from a group comprising a diluent, a disintegrant, a sweetener, a binder, a levelling agent, a humectant or wetting agent, a lubricant, a flavoring agent, a dye, and mixtures thereof, said mixture of excipients preferably coming in the form of grains.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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